Abstract Long-term pain is A serious supply of morbidity for which there are restricted powerful therapies. Palmitoylethanolamide (PEA), a The natural way taking place fatty acid amide, has shown utility inside the remedy of neuropathic and inflammatory discomfort. Emerging experiences have supported a feasible position for its use in the therapy o
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PEA guards versus bacterial infection by using innate immune modulation involving MCs, macrophages and microglia. Prophylactic PEA at a dose of 0.1 mg/kg body body weight extended survival level and reduced neuro-inflammation within an aged murine bacterial meningitis design, within the absence of antibiotics [42].Palmitoylethanolamide (PEA) contin
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